Responders and non-responders in cognitive rehabilitation (WFNR)


Le 01/12/2022 de 17:00 à 18:30


Retour Session

CO152

Etude pilote: Effets de la rTMS sur les processus temporels lors de tâches de dénomination chez des patients atteints d'aphasie chronique.
 

FRANCOISE DE MORSIER Tomy (Bordeaux, France)

Objective : Advances in cortical neuromodulation, particularly rTMS (repetitive Transcranial Magnetic Stimulation), suggest the possibility of optimizing recovery from aphasia. However, the rTMS effects on the temporal aspects in language processes remain poorly explored. These aspects are crucial to understand the disturbances at the linguistic level. The aim of this pilot study was to explore the changes in temporal processes via EEG/Event related potentials after right inhibitory or left excitatory rTMS.

 

Material / Patients and Methods : Six patients with chronic post-stroke aphasia, who had impairment predominantly in phonological features, from Bordeaux University hospital received right inhibitory or left excitatory rTMS, preceded and followed by a EEG recording (128 channel) during naming task. Behavioral and electrophysiological changes were explored.
 

Results : Language production was modified after left facilitation and phonological error decreased. On the same time, electrophysiological changes were observed in specific time windows of phonological processes. These changes were not observed after right inhibition.

 

Discussion - Conclusion : The literature suggests that the involvement of preserved perilesional areas in the left hemisphere may have a role in language recovery. Our results show that left facilitation permitted to decrease phonological errors for patient. Also, we note EEG changes in time windows corresponding to impaired processes. This study will provide results on the neurophysiological basis of the effect of rTMS in patients with aphasia
 

Keywords : rTMS, aphasia, EEG, ERP